“Navigating between the worlds of mechanistic and synthetic organic chemistry,” Jacobsen, E. N. Tetrahedron, submitted.

“Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α,” Hou, Y.; Nwachukwu, J. C.; Carlson, K.; Kim, S. H.; Angle, S.; Jacobsen, E. N.; Woods, T.; Mateus, S. L.; Fanning, S. W.; Ziegler, Y.; Katzenellenbogen, B. S.; Nettles, K. W.; Katzenellenbogen, J. A. ACS Pharmacol. Transl. Sci.  2025, in press (DOI: 10.1021/acsptsci.5c00117.

“Selective Noncovalent Catalysis with Small Molecules,” Sak, M. H.; Jacobsen, E. N. Chem. Review  2025, 125, in press (DOI: 10.1021/acs.chemrev.5c00121)

“Enantioselective Ring Opening of Azetidines via Charge Recognition in Hydrogen-Bond-Donor Catalysis,” Gair, J. J.; Isomura, M.; Wagen, C. C.; Strassfeld, D. A. J. Am. Chem. Soc.  2025, 147, 6378–6383.

“Computational Library Enables Pattern Recognition (‘Fingerprinting’) of Noncovalent Interactions and Application as a Modern Linear Free Energy Relationship,” Read, J. A.; Ball, T. E.; Miller, B.; Jacobsen, E. N. J. Org. Chem.  2024, 89, 17237–17247.

“Iterative Catalyst-Controlled Diastereoselective Matteson Homologations Enable the Selective Synthesis of Benzestrol Isomers,”Angle, S. R.; Sharma, H. A.; Choi, C. K.; Carlson, K. E.; Hou, Y.; Nwachukwu, J. C.; Kim, S. H., Katzenellenbogen, B. S.; Nettles, K. W.; Katzenellenbogen, J. A.; Jacobsen, E. N. J. Am. Chem. Soc.  2024, 146, 30771–30777.

“β-Selective 2-Deoxy- and 2,6-Dideoxyglucosylations Catalyzed by BisThioureas,”Beyer, P. D.; Nielsen, M. M.; Picazo, E.; Jacobsen, E. N. J. Am. Chem. Soc.  2024, 146, 27318–27323.

“Catalysis of an SN2 pathway by geometric preorganization,”Lovinger, G. J.; Sak, M. H.; Jacobsen E. N. Nature  2024, 632, 1052–1059.

“Enantioselective Potassium-Catalyzed Wittig Olefinations,” Essman, J. Z.; Jacobsen, E. N. J. Am. Chem. Soc.  2024, 146, 7165-7172.

“Development of Enantioselective Lithium-Isothiourea-Boronate-Catalyzed Matteson Homologations,” [Published as part of the Cluster Modern Boron Chemistry: 60 Years of the Matteson Reaction], Essman, J. Z.; Sharma, H. A.; Jacobsen, E. N. Synlett  2023, 34, 2061-2070.

“Dual-Hydrogen-Bond Donor and Bronsted Acid Cocatalysis Enables Highly Enantioselective Protio-Semipinacol Rearrangement Reactions,” Blackburn, M. A. S; Wagen, C. C.; Bodrogean, M. R.; Tadross, P. M.; Bendelsmith, A. J.; Kutateladze, D. A.; Jacobsen, E. N. J. Am. Chem. Soc.  2023, 145, 15036−15042.

“Enantioselective Transition-Metal Catalysis via an Anion-Binding Approach,” Ovian, J. M.; Vojáčková, P.; Jacobsen, E. N. Nature  2023, 616, 84-89.

“Andreas Pfaltz, Inspiration and Friend,” Jacobsen, E.N. Adv. Synth. Catal.  2022, 364, 3324.

“Evidence for Oxonium Ions in Ethereal ‘Hydrogen Chloride’,” Wagen, C. C.; Jacobsen, E.N. Organic Lett.  2022, 24, 8826-8831.

“Exploring Structure–Function Relationships of Aryl Pyrrolidine-Based Hydrogen-Bond Donors in Asymmetric Catalysis using Data-Driven Techniques,” Mohammad, S.; Hofstra Wahlman, J.; Read, J.; Werth, J.; Jacobsen, E.N.; Sigman, M. S.; ACS Catal.  2022, 12, 14836–14845.

“Screening for Generality in Asymmetric Catalysis,” Wagen, C. C.; McMinn, S. E.; Kwan, E. E.; Jacobsen, E.N. Nature  2022, 610, 680-686.

“Chloride-Mediated Alkene Activation Drives Enantioselective Thiourea and Hydrogen Chloride Co-Catalyzed Prins Cyclizations,” Kutateladze, D. A.; Wagen, C. C.; Jacobsen, E.N. J. Am. Chem. Soc.  2022, 144, 15812-15824.

“Site-Selective, Stereocontrolled Glycosylation Catalyzed by Bis-Thioureas,” Li, Q.; Levi, S. M.; Wagen, C. C.; Wendlandt, A. E; Jacobsen, E.N. Nature  2022, 608, 74-79.

“Enantioselective hydrogen-bond-donor catalysis to access diverse stereogenic-at-P(V) compounds,” Forbes, K.A.; Jacobsen, E.N. Science  2022, 376, 1230-1236.

“Catalytic Alkene Difunctionalization Reactions,”Ovian, J.M.; Jacobsen, E.N. in Iodine Catalysis in Organic Synthesis  Ishihara, K., Muniz, K., Eds; Wiley-VCH GmbH: Weinheim, Ch.9,  243-274.

“Chiral Ureas, Thioureas, and Squaramides in Anion-Binding Catalysis with Co-catalytic Bronsted/Lewis Acids,” Trotta, A.; Jacobsen, E.N. in Anion Binding Catalysis   Garcia Mancheno, O., Eds.;Wiley-VCH GmbH: Weinheim, Ch.4,  9585-9594.

“Cooperative Hydrogen-Bond-Donor Catalysis with Hydrogen Chloride Enables Highly Enantioselective Prins Cyclization Reactions,” Kutateladze, D.A.; Jacobsen, E.N. J. Am. Chem. Soc.  2021, 143, 20077-20083.

“Enantioselective catalytic 1,2-boronate rearrangements,” Sharma, H.A.; Essman, J.Z.; Jacobsen, E.N. Science  2021, 374, 752-757.

“A Case Study in Catalyst Generality: Simultaneous Highly-Enantioselective Bronsted- and Lewis-Acid Mechanisms in Hydrogen-Bond-Donor Catalyzed Oxetane Openings,” Strassfeld, D.A.; Algera, R.F.; Wickens, Z.K.; Jacobsen, E.N. J. Am. Chem. Soc.  2021, 143, 9585-9594.

“Enantioselective, Catalytic Multicomponent Synthesis of Homoallylic Amines Enabled by Hydrogen-Bonding and Dispersive Interactions,” Ronchi, E.; Paradine, S.M.; Jacobsen, E.N. J. Am. Chem. Soc.  2021, 143, 7272-7278.

“The Aryl-Pyrrolidine-tert-Leucine Motif as a New Privileged Chiral Scaffold: The Role of Non-Covalent Stabilizing Interactions,” Strassfeld, D.A.; Jacobsen, E.N., in Supramolecular Catalysis: New Directions and Developments, van Leeuwen, Raynal, Eds.; Wiley, New York, ISBN 978-3-527-34902-9, Chapter 25.

“Enantioselective Aryl-Iodide-Catalyzed Wagner–Meerwein Rearrangements,”Sharma, H.A.; Mennie, K.M.; Kwan, E.E.; Jacobsen, E.N. J. Am. Chem. Soc.  2020, 142, 16090-16096.

“Catalytic Enantioselective Synthesis of Difluorinated Alkyl Bromides,”Levin, M.D.; Ovian, J.M.; Read, J.A.; Sigman, M.S.; Jacobsen, E.N. J. Am. Chem. Soc.  2020, 142, 14831–14837.

“Asymmetric Nazarov Cyclizations of Unactivated Dienones by Hydrogen-Bond-Donor/Lewis Acid Co-Catalyzed, Enantioselective Proton-Transfer,” Metternich, J.; Reiterer, M.; Jacobsen, E.N. Adv. Synth. Catal. 2020, 362, 4092-4097.

“Highly Selective β-Mannosylations and β-Rhamnosylations Catalyzed by Bis-thiourea,” Li, Q.; Levi, S.M.; Jacobsen, E.N. J. Am. Chem. Soc.  2020, 142, 11865-11872.

“Highly Enantioselective, Hydrogen-Bond-Donor Catalyzed Additions to Oxetanes,” Strassfeld, D.A.; Wickens, Z.K.; Picazo, E.; Jacobsen, E.N. J. Am. Chem. Soc.  2020, 142, 9175-9180.

“Enantioselective Tail-to-Head Cyclizations Catalyzed by Dual-Hydrogen-Bond Donors,” Kutateladze, D.A, Strassfeld, D.A.; Jacobsen, E.N. J. Am. Chem. Soc.  2020, 142, 6951-6956.

“Enantioselective Catalysis of an Anionic Oxy-Cope Rearrangement Enabled by Synergistic Ion Binding,” Kennedy,C.R.; Choi, B.Y.; Reeves, M.G.R.; Jacobsen, E.N. Israel J.Chem. 2020, 60, 461-474. (Special issue in honor of Stephen Buchwald and John Hartwig)

“Stereospecific Furanosylations Catalyzed by Bis-Thiourea Hydrogen-Bond Donors,” Mayfield, A.B.; Metternich, J.B.; Trotta, A.H.; Jacobsen, E.N. J. Am. Chem. Soc.  2020, 142, 4061-4069.

“A Catalytic One-Two Punch,” Ovian, J.M.; Jacobsen, E.N. Science  2019, 366, 948-949 (Perspective).

“Catalyst-Controlled Glycosylations,” Levi, S.M.; Jacobsen, E.N. Organic Reactions  2019, 100, 801-852.

“Enantioselective Synthesis of α-Allyl Amino Esters via Hydrogen-Bond Donor Catalysis,” Bendelsmith, A.J.; Kim, S.C.; Wasa, M.; Roche, S.P.; Jacobsen, E.N. J. Am. Chem. Soc.  2019, 141, 11414-11419.

“Catalytic, Enantioselective 1,2 Difluorination of Cinnamamides,” Haj, .K.; Banik, S.M.; Jacobsen, E.N. Org. Lett.  2019, 21, 4919-4923.

“Catalytic Activation of Glycosyl Phosphates for Stereoselective Coupling Reactions,” Levi, S.M.; Li, Q.; Roetheli, A.R.; Jacobsen, E.N. Proc. Natl. Acad. Sci. USA  2019, 116, 35-39.

“Mechanism and Origins of Chemo-and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes,” Zhou, B.; Haj, M.K.; Jacobsen, E.N.; Houk, K.N.; Xue, X.S. J. Am. Chem. Soc.  2018, 140, 15206-15218.

“Concerted nucleophilic aromatic substitutions,” Kwan, E.E.; Zeng, Y.; Besser, H.A.; Jacobsen, E.N. Nature Chem.  2018,10 , 917-923.

“Quaternary Stereocenters via an Enantioconvergent Catalytic SN1 Reaction,” Wendlandt, A.E.; Vangal, P.; Jacobsen, E.N. Nature  2018, 556 , 447-451.

“Catalytic Diastereo-and Enantioselective Fluoroamination of Alkenes,” Mennie, K.M., Banik, S.M.; Reichert, E.C., Jacobsen, E.N. J.Am.Chem.Soc.  2018, 140 , 4797-4802.

“Lewis Acid Enhancement by Hydrogen-Bond Donors for Asymmetric Catalysis,” Banik, S.M.; Levina, A.; Hyde, A. M.; Jacobsen, E.N. Science  2017, 358 , 761-764.

“Chiral Thioureas Promote Enantioselective Pictet–Spengler Cyclization by Stabilizing Every Intermediate and Transition State in the Carboxylic Acid-Catalyzed Reaction,” Klausen, R. S.; Kennedy, C. R.; Hyde, A. M.; Jacobsen, E.N J. Am. Chem. Soc.  2017, 139 , 12299-12309.

“Catalytic 1,3-Difunctionalization via Oxidative C–C Bond Activation,” Banik, S.M.; Mennie, K.; Jacobsen, E.N. J. Am. Chem. Soc.  2017, 139, 9152-9155.

“Sensitive and Accurate ¹³C Kinetic Isotope Effect Measurements Enabled by Polarization Transfer,” Kwan, E.E.; Park, Y.; Besser, H.A.; Anderson, T.L.; Jacobsen, E.N. J. Am. Chem. Soc.  2017, 139 (1) , 43-46.

“Macrocyclic Bis-Thioureas Catalyze Stereospecific Glycosylation Reactions,” Park, Y.; Harper, K.C.; Kuhl, N.; Kwan, E.E.; Liu, R.Y.; Jacobsen, E.N. Science 2017, Vol. 355, Issue 6321, 162-166.

“Enantioselective Aza-Sakurai Cyclizations: Dual Role of Thiourea as H-bond Donor and Lewis Base,” Park, Y.; Schindler, C.S.; Jacobsen, E.N. J. Am. Chem. Soc. 2016, 138, 14848-14851.

“Enantioselective, Catalytic Fluorolactonization Reactions with a Nucleophilic Fluoride Source,” Woerly, E.M.; Banik, S.M.; Jacobsen, E.N. J. Am. Chem. Soc.  2016, 138, 13858-13861.

“Mechanism-Guided Development of a Highly Active, Dimeric Thiourea Catalyst for Anion-Abstraction Catalysis,” Kennedy, C.R.; Lehnherr, D.; Rajapaksa, N.S.; Ford, D.D.; Park, Y.; Jacobsen, E.N. J. Am. Chem. Soc.  2016, 138, 13525-13528.

“Conformational Control of Chiral Amido-Thiourea Catalysts Enables Improved Activity and Enantioselectivity,” Lehnherr, D.; Ford, D.D.; Bendelsmith, A.; Kennedy, C.R.; Jacobsen, E.N. Org. Lett. 2016, 18, 3214-3217.

“Anion-Abstraction Catalysis: The Cooperative Mechanism of α-Chloroether Activation by Dual H-Bond Donors,” Ford, D.D.; Lehnherr, D.; Kennedy, C.R.; Jacobsen, E.N. ACS Catal. 2016, 6, 4616-4620.

“On-and Off-Cycle Catalyst Cooperativity in Anion-Binding Catalysis,” Ford, D.D.; Lehnherr, D.; Kennedy, C.R.; Jacobsen, E.N. J. Am. Chem. Soc. 2016, 138, 7860-7863.

“Organometallic Chemistry: A New Metathesis,” Hennessy, E.T.; Jacobsen, E.N. Nature Chem.  2016, 8, 741-742.

“Catalytic Asymmetric Difluorination of Alkenes to Generate Difluoromethylated Stereocenters,” Banik, S.M.; Medley, J.W.; Jacobsen, E.N. Science 2016, 353, 51-54.

“Synergistic Ion-Binding Catalysis Demonstrated via an Enantioselective, Catalytic [2,3]-Wittig Rearrangement, ” Kennedy, C.R.; Guidera, J.A.; Jacobsen, E.N. ACS Cent. Sci.  2016, 2, 416-423.

“Catalytic, Diastereoselective 1,2-Difluorination of Alkenes,” Banik, S.M.; Medley, J.W.; Jacobsen, E. N. J. Am. Chem. Soc.  2016, 138,5000-5003.

“The cation-π Interaction in Small-Molecule Catalysis” Kennedy, C.R.; Lin, S.; Jacobsen, E. N. Angew. Chem. Int. Ed. ,in press. doi: 10.1002/anie.201600547R1(Review)

“Activation of Electron-Deficient Quinones through Hydrogen-Bond-Donor-Coupled Electron Transfer,” Turek, A.K.; Hardee, D.M.; Ullman, A.; Nocera, D.C.; Jacobsen, E. N. Angew. Chem. Ed. 2016, 55,539-544 [Angew. Chem. 2016128,549-554]

“A Simple Primary Amine Catalyst for Enantioselective α-Hydroxylations and α-Fluorinations of Branched Aldehydes,” Witten, M.R.; Jacobsen, E. N. Organic Lett.

“Enantioselective synthesis of tertiary α-chloro esters by non-covalent catalysis,” Liu, R.Y.; Wasa, M.; Jacobsen, E. N. Tetrahedron Lett. 2015, 56,3428-3430 (Special issue honoring Harry Wasserman)

“Highly Enantioselective, Intermolecular Hydroamination of Allenyl Esters Catalyzed by Bifunctional Phosphinothioureas,” Fang, Y.-Q.; Tadross, P.M.; Jacobsen, E.N. J. Am. Chem. Soc. 2014, 136, 17966-17968 [Supporting Information]

“Enantioselective Selenocyclization via Dynamic Kinetic Resolution of Seleniranium Ions by Hydrogen-Bond Donor Catalysts” Zhang, H.; Lin, S.; Jacobsen, E. N. J. Am. Chem. Soc. 2014, 136, 16485-16488 [Supporting Information]

Jacobsen, E. N.; Zuend, S. J. "Compound reagents and method for synthesizing enantiomerically enriched amino acids," U.S. Patent #8859812, October 14, 2014.

“Thiourea-Catalyzed Enantioselective Addition of Indoles to Pyrones: Alkaloid Cores with Quaternary Carbons” Yeung, C. S.; Ziegler, R. E.; Porco, J. A., Jr.; Jacobsen, E. N. J. Am. Chem. Soc. 2014, 136, 13614-13617 [Supporting Information]

“Asymmetric Mannich Synthesis of α-Amino esters by Anion-Binding Catalysis” Wasa, M,; Liu, R. Y.; Roche, S. P.; Jacobsen, E. N. J. Am. Chem. Soc. 2014, 136, 12872-12875 [Supporting Information]

“Chiral sulfinamidourea and strong Brønsted acid–cocatalyzed enantioselective Povarov reaction to access tetrahydroquinolines” Xu, H.; Zhang, H.; Jacobsen, E. N. Nat. Protoc. 2014, 9, 1860-1866.

“Catalytic Asymmetric Synthesis of 8-Oxabicyclooctanes by Intermolecular [5+2] Pyrylium Cycloadditions” Witten, M. R.; Jacobsen, E. N. Angew. Chem. Int. Ed. 2014, 53, 5912-5916. [Supporting Information]

“A broadly applicable and practical oligomeric salen(Co) catalyst for enantioselective epoxide ring-opening reactions,” White, D. E.; Tadross, P. M.; Lu, Z.; Jacobsen, E. N. Tetrahedron 2014, 70, 4165-4180.

“Photoredox Activation and Anion-Binding in the Dual Catalytic Enantioselective Synthesis of β-Amino Esters” Bergonzini, G.; Schindler, C. S.; Wallentin, C.-J.; Jacobsen, E. N.; Stephenson, C. R. J. Chem. Sci. 2014, 5, 112-116. [Supporting Information]

“Mechanistic Basis for High Selectivity and Broad Substrate Scope in the (salen)Co(III)-Catalyzed Hydrolytic Kinetic Resolution” Ford, D. D.; Nielsen, L. P. C.; Zuend, S. J.; Musgrave, C. B.; Jacobsen, E. N. J. Am. Chem. Soc. 2013,135, 15595-15608. [Supporting Information]

“Enantioselective Catalytic Transannular Ketone Ene Reactions”  Rajapaksa, N.S.; Jacobsen, E. N. Org. Lett. 2013, 15, 4238–4241.  [Supporting Information]

“A Practical Method for the Synthesis of Highly Enantioenriched trans-1,2-Amino Alcohols” Birrell, J. A.; Jacobsen, E. N. Org. Lett. 2013, 15, 2895–2897.  [Supporting Information]

“A New Twist on Cooperative Catalysis”  Schindler, C. S.; Jacobsen, E. N. Science 2013, 340, 1052–1053 (Perspective).

“Enantioselective Thiourea-Catalyzed Intramolecular Cope-Type Hydroamination” Brown, A. R.; Uyeda, C.; Brotherton, C. A.; Jacobsen, E. N. J. Am. Chem. Soc. 2013, 135, 6747–6749. [Supporting Information]

“Chiral β-Iodoamines by Urea-Catalysed Iodocyclization of Trichloroacetimidates”  Brindle, C. S.; Yeung, C. S.; Jacobsen, E. N.  Chem. Sci. 2013, 4, 2100–2104.  [Supporting Information]

“Enantioselective Formal Aza-Diels–Alder Reactions of Enones with Cyclic Imines Catalyzed by Primary Aminothioureas” Lalonde, M. P.; McGowan, M. A.; Rajapaksa, N. S.; Jacobsen, E. N. J. Am. Chem. Soc. 2013, 135, 1891–1894. [Supporting Information]

“Enantioselective Total Synthesis of (+)-Reserpine” Rajapaksa, N. S.; McGowan, M. A.; Rienzo, M.; Jacobsen, E. N. Org. Lett. 2013, 15, 706–709.  [Supporting Information]

“Asymmetric Ion-Pairing Catalysis”  Brak, K.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2013, 52, 534–561.

“Remodelling by diversity and design”  Tadross, P. M.; Jacobsen, E. N. Nature Chem. 2012, 4, 963–965 (News & Views).

“Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahyroquinoline Library”  Gerard, B; O’Shea, M. W.; Donckele, E.; Kesavan, S.; Akella, L. B.; Xu, H.; Jacobsen, E. N.; Marcaurelle, L. A. ACS Comb. Sci. 2012, 14, 621–630. [Supporting Information]

“Thiourea-catalysed ring opening of episulfonium ions with indole derivatives by means of stabilising, non-covalent interactions”  Lin, S.; Jacobsen, E. N. Nature Chem. 2012, 4, 817–824. [Supporting Information]

“Catalysis in Tight Spaces” Burns, N. Z.; Jacobsen, E. N. Nature 2012, 483, 278–279 (News & Views).

“Mechanistic Basis for High Reactivity of (salen)Co-OTs in the Hydrolytic Kinetic Resolution of Terminal Epoxides” Nielsen, L. P. C.; Zuend, S. J.; Ford, D. D.; Jacobsen, E. N. J. Org. Chem. 2012, 77, 2486–2495. [Supporting Information]

"Thiourea-Catalyzed Enantioselective Iso-Pictet–Spengler Reactions” Lee, Y.; Klausen, R. S.; Jacobsen, E. N. Org. Lett. 2011, 13, 5564–5567. [Supporting Information]

"Dual Catalysis in Enantioselective Oxidopyrylium-Based [5 + 2] Cycloadditions” Burns, N. Z.; Witten, M. R.; Jacobsen, E. N. J. Am. Chem. Soc. 2011, 133, 14578–14581. [Supporting Information]

"Enantioselective Acylation of Silyl Ketene Acetals through Fluoride Anion-Binding Catalysis" Birrell, J. A.; Desrosiers, J.-N.; Jacobsen, E. N. J. Am. Chem. Soc. 2011, 133, 13872–13875. [Supporting Information]

"Chiral Sulfinamide/Achiral Sulfonic Acid Cocatalyzed Enantioselective Protonation of Enol Silanes" Beck, E. M.; Hyde A. M.; Jacobsen E. N. Org. Lett. 2011, 13, 4260–4263. [Supporting Information]

"Transition State Charge Stabilization Through Multiple Non-Covalent Interactions in the Guanidinium-Catalyzed Enantioselective Claisen Rearrangement"  Uyeda, C.; Jacobsen, E. N. J. Am. Chem. Soc. 2011, 133, 5062–5075. [Supporting Information]

"Catalytic Enantioselective Claisen Rearrangements of O-Allyl β-Ketoesters"  Uyeda, C.; Rötheli, A. R.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2010, 49, 9753–9756. [Supporting Information]

Burns, N. Z.; Jacobsen, E. N. Mannich Reaction. In Stereoselective Synthesis 2: Stereoselective Reactions of Carbonyl and Imino Groups; Molander, G., Ed.; Georg Thieme Verlag: New York, 2010; Chapter 2.16.

"Organocatalysis" Jacobsen, E. N.; MacMillan, D. W. C. Proc. Natl. Acad. Sci. USA 2010, 107, 20618–20619.

"Attractive Non-Covalent Interactions in Asymmetric Catalysis: Links Between Enzymes and Small-Molecule Catalysts" Knowles, R. R.; Jacobsen, E. N. Proc. Natl. Acad. Sci. USA 2010, 107, 20678–20685.

"Tertiary Aminourea-Catalyzed Enantioselective Iodolactonization" Veitch, G. E.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2010, 49, 7332–7335.  [Supporting Information]

"Enantioselective Catalytic α-Alkylation of Aldehydes via an SN1 Pathway" Brown, A. R.; Kuo, H.-S.; Jacobsen, E. N. J. Am. Chem. Soc. 2010, 132, 9286–9288.  [Supporting Information]

"An Enantioselective Total Synthesis of (+)-Peloruside A" McGowan, M. A.; Stevenson, C. P.; Schiffler, M. A.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2010, 49, 6147–6150. [Supporting Information]

"Enantioselective Thiourea-Catalyzed Cationic Polycyclizations” Knowles, R. R.; Lin, S.; Jacobsen, E. N. J. Am. Chem. Soc. 2010, 132, 5030–5032. [Supporting Information]

"Asymmetric Cooperative Catalysis of Strong Brønsted Acid-Promoted Reactions Using Chiral Ureas” Xu, H.; Zuend, S. J.; Woll, M. P.; Tao, Y.; Jacobsen, E. N. Science 2010, 327, 986–990. [Supporting Information]

"Mechanism of Amido-Thiourea Catalyzed Enantioselective Imine Hydrocyanation: Transition State Stabilization via Multiple Non-Covalent Interactions"  Zuend, S. J., Jacobsen, E. N. J. Am. Chem. Soc. 2009, 131, 15358–15374. [Supporting Information]

"Scaleable catalytic asymmetric Strecker syntheses of unnatural α-amino acids" Zuend, S. J.; Coughlin, M. P.; Lalonde, M. P.; Jacobsen, E. N. Nature 2009, 461, 968–970. [Supporting Information]

"Enantioselective, Thiourea-Catalyzed Intermolecular Addition of Indoles to Cyclic N-Acyl Iminium Ions" Peterson, E. A.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2009, 48, 6328–6331. [Supporting Information]

"Bifunctional Asymmetric Catalysis with Hydrogen Chloride: Enantioselective Ring Opening of Aziridines Catalyzed by a Phosphinothiourea" Mita, T.; Jacobsen, E. N. Synlett  2009, 1680–1684 (Special Cluster Issue on Cooperative Catalysis).

"Enantioselective Intramolecular Openings of Oxetanes Catalyzed by (salen)Co(III) Complexes: Access to Enantioenriched Tetrahydrofurans" Loy, Rebecca N.; Jacobsen, E. N. J. Am. Chem. Soc. 2009, 131, 2786–2787. [Supporting Information]

"Weak Brønsted Acid-Thiourea Co-catalysis: Enantioselective, Catalytic Protio-Pictet–Spengler Reactions" Klausen, R. S.; Jacobsen, E. N. Org. Lett. 2009, 11, 887–890. [Supporting Information]

"Structural Analysis of Spiro β-Lactone Proteasome Inhibitors" Groll, M.; Balskus, E. P.; Jacobsen, E. N.  J. Am. Chem. Soc. 2008, 130, 14981–14983. [Supporting Information]

"Asymmetric Intramolecular Arylcyanation of Unactivated Olefins via C–CN Bond Activation”  Watson, M. P.; Jacobsen, E. N.  J. Am. Chem. Soc. 2008, 130, 12594–12595. [Supporting Information]

"Enantioselective Claisen Rearrangements with a Hydrogen-Bond Donor Catalyst"  Uyeda, C.; Jacobsen, E. N.  J. Am. Chem. Soc. 2008, 130, 9228–9229. [Supporting Information]

"Enantioselective Thiourea-Catalyzed Additions to Oxocarbenium Ions" Reisman, S. E.; Doyle, A. G.; Jacobsen, E. N. J. Am. Chem. Soc. 2008, 130, 7198–7199. [Supporting Information]

"Cooperative, Highly Enantioselective Phosphinothiourea Catalysis of Imine-Allene [3+2] Cycloadditions" Fang, Y.-Q.; Jacobsen, E. N. J. Am. Chem. Soc. 2008, 130, 5660–5661. [Supporting Information]

"Regio- and Enantioselective Cyclization of Pyrroles onto N-Acyliminium Ions" Raheem, I. T.; Thiara, P. V.; Jacobsen, E. N.  Org. Lett. 2008, 10, 1577–1580. [Supporting Information]

"Cooperative Catalysis in the Hydrolytic Kinetic Resolution of Epoxides by Chiral [(salen)CoIII] Complexes Immobilized on Gold Colloids"  Belser, T.; Jacobsen, E. N.  Adv. Synth. Catal. 2008, 350, 967–971.

"Catalytic Asymmetric Total Synthesis of (+)-Yohimbine" Mergott, D. J.; Zuend, S. J.; Jacobsen, E. N. Org. Lett. 2008, 10, 745–748. [Supporting Information]

"Dimeric (salen)Al Complexes Display Expanded Scope in the Conjugate Cyanation of a β-Unsaturated Imides" Mazet, C.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2008, 47, 1762–1765. [Supporting Information]

"Enantioselective Catalytic Carbonyl-ene Cyclization Reactions" Grachan, M. L.; Tudge, M. T.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2008, 47, 1469–1472. [Supporting Information]

"Small-Molecule H-Bond Donors in Asymmetric Catalysis"  Doyle, A. G.; Jacobsen, E. N.  Chem. Rev. 2007, 107, 5713–5743.

"Cooperative Catalysis by Tertiary Amino-Thioureas: Mechanism and Basis for Enantioselectivity of Ketone Cyanosilylation" Zuend, S. J.; Jacobsen, E. N.  J. Am. Chem. Soc. 2007, 129, 15872–15883. [Supporting Information]

"Enantioselective Pictet–Spengler-Type Cyclizations of Hydroxylactams: H-Bond Donor Catalysis by Anion Binding" Raheem, I. T.; Thiara, P. V.; Peterson, E. A.; Jacobsen, E. N.  J. Am. Chem. Soc. 2007, 129, 13404–13405. [Supporting Information]

"Asymmetric Catalysis of the Transannular Diels–Alder Reaction" Balskus, E. P.; Jacobsen, E. N. Science 2007, 317, 1736–1740. [Supporting Information]

"Enantioselective Alkylation of Acyclic α,α-Disubstituted Tributyltin Enolates Catalyzed by a {Cr(salen)} Complex" Doyle, A. G.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2007, 46, 3701–3705. [Supporting Information]

"Indium-Mediated Asymmetric Allylation of Acylhydrazones Using a Chiral Urea Catalyst"  Tan, K. L.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2007, 46, 1315–1317. [Supporting Information]

"Alk-2-enoic Acid Esters” Vanderwal, C. D.; Jacobsen, E. N. Science of Synthesis 2006, 20b, 1305–1340.

"Arenecarboxylic Acid Esters" Yoon, T. P.; Jacobsen, E. N.  Science of Synthesis 2006, 20b, 1285–1304.

"Alk-2-enoic Acids" Vanderwal, C. D.; Jacobsen, E. N.  Science of Synthesis 2006, 20a, 551–568.

"Arenecarboxylic Acids" Yoon, T. P.; Jacobsen, E. N.  Science of Synthesis 2006, 20a, 533–549.

"Preparation of (S)-Methyl Glycidate via Hydrolytic Kinetic Resolution" Stevenson, C. P.; Nielsen, L. P. C. Jacobsen, E. N. Org. Synth. 2006, 83, 162–166.

"A Chiral Primary Amine-Thiourea Catalyst for the Highly Enantioselective Direct Conjugate Addition of α,α-Disubstituted Aldehydes to Nitroalkenes"  Lalonde, M. P.; Chen, Y.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2006, 45, 6366–6370. [Supporting Information]

"Highly Enantioselective Direct Conjugate Addition of Ketones to Nitroalkenes Promoted by A Chiral Primary Amine-Thiourea Catalyst" Huang, H.; Jacobsen, E. N. J. Am. Chem. Soc. 2006, 128, 7170–7171. [Supporting Information]

"α,β-Unsaturated β-Silyl Imide Substrates for Catalytic, Enantioselective Conjugate Additions: A Total Synthesis of (+)-Lactacystin and the Discovery of a New Proteasome Inhibitor" Balskus, E. P.; Jacobsen, E. N. J. Am. Chem. Soc. 2006, 128, 6810–6812. [Supporting Information]

"Asymmetric Catalysis by Chiral Hydrogen Bond Donors" Taylor, M. S.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2006, 45, 1520–1543.

Nielsen, L. P. C. Jacobsen, E. N. Catalytic, Asymmetric Epoxide Ring-Opening Chemistry. In Aziridines and Epoxides in Organic Synthesis; Yudin, A., Ed.; Wiley: New York, 2006; Chapter 10.

"An Efficient, Highly Diastereo- and Enantioselective Hetero-Diels-Alder Catalyst. Preparation of (2S,6R)-6-(tert-Butyldimethylsilyloxymethyl)-2-Methoxy-2,5-Dihydropyran" Chavez, D. E.; Jacobsen, E. N.  Org. Synth. 2005, 82, 34–42.

"Highly Enantioselective Aza-Baylis–Hillman Reactions Catalyzed by Chiral Thiourea Derivatives" Raheem, I. T.; Jacobsen, E. N.  Adv. Synth. Catal. 2005, 347, 1701–1708.  [Supporting Information]

"Enantioselective Thiourea-Catalyzed Acyl-Mannich Reactions of Isoquinolines" Taylor, M. S.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2005, 44, 6700–6704. [Supporting Information]

"Efficient Total Syntheses of (–)-Colombiasin A and (–)-Elisapterosin B: Application of the Cr-Catalyzed Asymmetric Quinone Diels–Alder Reaction" Boezio, A. A.; Jarvo, E. R.; Lawrence, B. M.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2005, 44, 6046–6050.  [Supporting Information]

"Highly Enantio- and Regioselective Quinone Diels–Alder Reactions Catalyzed by a Tridentate (Schiff Base)Cr(III) Complex" Jarvo, E. R.; Lawrence, B. M.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2005, 44, 6043–6046.  [Supporting Information]

"Thiourea-Catalyzed Enantioselective Cyanosilylation of Ketones" Fuerst, D. E.; Jacobsen, E. N.  J. Am. Chem. Soc. 2005, 127, 8964–8965.  [Supporting Information]

Wenzel, A. G.; Jacobsen, E. N. Asymmetric Catalysis in the Enantioselective Synthesis of β-Amino Acids. In Enantioselective Synthesis of beta-Amino Acids; Juaristi, E., Soloshonok, V., Eds.; Wiley-VCH: New York, 2005; Chapter 4.

"Highly Enantioselective Catalytic Conjugate Addition of N-Heterocycles to α,β-Unsaturated Ketones and Imides" Gandelman, M.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2005, 44, 2393–2397.  [Supporting Information]

"Highly Enantioselective Conjugate Additions to α,β-Unsaturated Ketones Catalyzed by a (salen)Al Complex"  Taylor, M. S.; Zalatan, D. N.; Lerchner, A. M.; Jacobsen, E. N.  J. Am. Chem. Soc. 2005, 127, 1313–1317.  [Supporting Information]

Jacobsen, E. N.; Sigman, M. S. Main Group Metal-Based Asymmetric Catalysts and Applications Thereof.  U.S. Patent #6844448, January 18, 2005.

"Highly Enantioselective Thiourea-catalyzed Nitro-Mannich Reaction" Yoon, T. P.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2005, 44, 466–468.  [Supporting Information]

"Enantioselective Alkylations of Tributyltin Enolates Catalyzed by Cr(salen)Cl: Access to Enantiomerically Enriched All Carbon Quaternary Centers"  Doyle, A. G.; Jacobsen, E. N.  J. Am. Chem. Soc. 2005, 127, 62–63.  [Supporting Information]

Jacobsen, E. N.; Tokunaga, M.; Larrow, J. F.  Hydrolytic Kinetic Resolution of Cyclic Substrates.  U.S. Patent #6800766, October 5, 2004.

"Highly Enantioselective Hydration of α,β-Unsaturated Imides by Al-Catalyzed Conjugate Addition of Oxime Nucleophiles"  Vanderwal, C. D.; Jacobsen, E. N.  J. Am. Chem. Soc. 2004, 126, 14724–14725.  [Supporting Information]

"Highly Enantioselective Catalytic Acyl-Pictet–Spengler Reactions"  Taylor, M. S.; Jacobsen, E. N.  J. Am. Chem. Soc. 2004, 126, 10558–10559.  [Supporting Information]

"Cooperative Dual Catalysis: Application to the Highly Enantioselective Conjugate Cyanation of Unsaturated Imides"  Sammis, G. M.; Danjo, H.; Jacobsen, E. N.  J. Am. Chem. Soc. 2004, 126, 9928–9929.  [Supporting Information]

"General Catalytic Synthesis of Highly Enantiomerically Enriched Terminal Aziridines from Racemic Epoxides"  Kim, S.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2004, 43, 3952–3954.  [Supporting Information]

"Asymmetric Processes Catalyzed by Chiral (Salen)Metal Complexes”  Larrow, J. F.; Jacobsen, E. N.  Top. Organomet. Chem. 2004, 6, 123–152.

Jacobsen, E. N.; Sigman, M. S.  Parallel Combinatorial Approach to the Discovery and Optimization of Catalysts and Uses Thereof.  U.S. Patent #6709824 B2, March 23, 2004.

"Asymmetric Catalysis in Complex Target Synthesis"  Taylor, M. S.; Jacobsen, E. N.  Proc. Nat. Acad. Sci. USA  2004, 101, 5368–5373.

"Thiourea-Catalyzed Enantioselective Hydrophosphonylation of Imines: Practical Access to Enantiomerically Enriched α-Amino Phosphonic Acids"  Joly, G. D.; Jacobsen, E. N.  J. Am. Chem. Soc. 2004, 126, 4102–4103.  [Supporting Information]

Liu, Y.; DiMare, M.; Marchese, S. A.; Jacobsen, E. N.; Jasmin, S.  Hydrolytic Kinetic Resolution of Epoxides.  U.S. Patent #6693206, February 17, 2004.

"Mechanistic Investigation Leads to a Synthetic Improvement in the Hydrolytic Kinetic Resolution of Terminal Epoxides"  Nielsen, L. C. P.; Stevenson, C. P.; Blackmond, D.G.; Jacobsen, E. N.  J. Am. Chem. Soc. 2004, 126, 1360–1362.  [Supporting Information]

"Catalytic Asymmetric Total Syntheses of Quinine and Quinidine"  Raheem, I. T.; Goodman, S. N.; Jacobsen, E. N.  J. Am. Chem. Soc. 2004, 126, 706–707.  [Supporting Information]

"Asymmetric Hydrocyanation of Hydrazones Catalyzed by Lanthanide - PYBOX Complexes”  Keith, J. M.; Jacobsen, E. N.  Org. Lett. 2004, 6, 153–155.  [Supporting Information]

Vachal, P.; Jacobsen, E. N.  Cyanation of Carbonyl and Imino Groups.  In Comprehensive Asymmetric Catalysis (1st Supplement); Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds.; Springer: New York, 2003; Chapter 28.

"New Oligomeric Catalyst for the Hydrolytic Kinetic Resolution of Terminal Epoxides Under Solvent-Free Conditions"  White, D. E.; Jacobsen, E. N. Tetrahedron: Asymm.  2003, 14, 3633–3638.  

"Asymmetric Hetero-Ene Reactions of Trimethylsilyl Enol Ethers Catalyzed by Tridentate Schiff Base Chromium(III) Complexes"  Ruck, R. T.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2003, 42, 4771–4774.  [Supporting Information]

"Divergent Stereoinduction Mechanisms in Urea-Catalyzed Additions to Imines"  Wenzel, A. G.; Lalonde, M. P.; Jacobsen, E. N.  Synlett 2003, 12, 1919–1922.

"Enantioselective Michael Additions to α,β-Unsaturated Imides Catalyzed by a Salen-Al Complex"  Taylor, M. S.; Jacobsen, E. N.  J. Am. Chem. Soc. 2003, 125, 11204–11205.  [Supporting Information]

"Catalyst-Controlled Inverse Electron Demand Hetero-Diels–Alder Reactions in the Enantio- and Diastereoselective Synthesis of Iridoid Natural Products"  Chavez, D. E.; Jacobsen, E. N.  Org. Lett. 2003, 5, 2563–2565.  [Supporting Information]

Jacobsen, E. N.; Sigman, M. S.  Main Group Metal-Based Asymmetric Catalysts and Applications Thereof.  U.S. Patent #6521561, February 18, 2003.

"Highly Enantioselective, Catalytic Conjugate Addition of Cyanide to α,β-Unsaturated Imides"  Sammis, G. M.; Jacobsen, E. N.  J. Am. Chem. Soc. 2003, 125, 4442–4443.  [Supporting Information]

"Privileged Chiral Catalysts"  Yoon, T. P.; Jacobsen, E. N.  Science 2003, 299, 1691–1693.

"Enantiopure β-Hydroxy Morpholine Amides From Terminal Epoxides via Carbonylation at 1 Atm”  Goodman, S. N.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2002, 41, 4703–4705.  [Supporting Information]

"The Simplest 'Enzyme'"  Movassaghi, M.; Jacobsen, E. N.  Science 2002, 298, 1904–1905 (Perspective).

"Asymmetric Catalytic Mannich Reactions Catalyzed by Urea Derivatives: Enantioselective Synthesis of β-Aryl-β-Amino Acids"  Wenzel, A. G.; Jacobsen, E. N.  J. Am. Chem. Soc. 2002, 124, 12964–12965.  [Supporting Information]

"A Practical Synthesis of α,β-Unsaturated Imides, Useful Substrates For Asymmetric Conjugate Addition Reactions"  Goodman, S. N.; Jacobsen, E. N.  Adv. Synth. Catal. 2002, 344, 953–956.

Jacobsen, E. N.; Tokunaga, M.; Larrow, J. F.  Hydrolytic Kinetic Resolution of Cyclic Substrates.  U.S. Patent #6448414, September 10, 2002.

"Structure-Based Analysis and Optimization of a Highly Enantioselective Catalyst for the Strecker Reaction"  Vachal, P.; Jacobsen, E. N.  J. Am. Chem. Soc. 2002, 124, 10012–10014.  [Supporting Information]

Jacobsen, E. N.; Francis, M. B.; Finney, N. S.  Combinatorial Approach for Generating Novel Coordination Complexes.  U.S. Patent #6489093, December 3, 2002.

"Highly Enantioselctive Inverse Electron Demand Hetero-Diels–Alder Reactions of α,β-Unsaturated Aldehydes"  Gademann, K.; Chavez, D. E.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2002, 41, 3059–3061.  [Supporting Information]

Jacobsen, E. N.; Schaus, S. E.; Dossetter, A. G.; Jamison, T. F.  Asymmetric Cycloaddition Reactions.  U.S. Patent #6369223, April 9, 2002.

"Catalyst-Controlled Diastereoselective Hetero-Diels–Alder Reactions"  Joly, G. D.; Jacobsen, E. N.  Org. Lett. 2002, 4, 1795–1798.  [Supporting Information]

"A Practical Oligomeric (salen)Co Catalyst for Asymmetric Epoxide Ring Opening Reactions"  Ready, J. R.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2002, 41, 1374–1377.  [Supporting Information]

"Asymmetric Catalysis of Hetero-Ene Reactions with Tridentate Schiff Base Chromium(III) Complexes"  Ruck, R. T.; Jacobsen, E. N.  J. Am. Chem. Soc. 2002, 124, 2882–2883.  [Supporting Information]

"A Direct Method for the Conversion of Terminal Epoxides into γ-Butanolides"  Movassaghi, M.; Jacobsen, E. N.  J. Am. Chem. Soc. 2002, 124, 2456–2457.  [Supporting Information]

"Highly Selective Hydrolytic Kinetic Resolution of Terminal Epoxides Catalyzed by Chiral (salen)Cobalt(III)-Complexes. Practical Synthesis of Enantioenriched Terminal Epoxides and 1,2-Diols"  Schaus, S. E.; Brandes, B. D; Larrow, J. F.; Tokunaga, M.; Hansen, K. B.; Gould, A. E.; Furrow, M. E.; Jacobsen, E. N.  J. Am. Chem. Soc. 2002, 124, 1307–1315.  [Supporting Information]

Jacobsen, E. N.; Sigman, M. S.  Parallel Combinatorial Approach to the Discovery and Optimization of Catalysts and Uses Thereof.  U.S. Patent #6316616, November 13, 2001.

"Total Synthesis of (+)-Ambruticin"  Liu, P.; Jacobsen, E. N.  J. Am. Chem. Soc. 2001, 123, 10772–10773.  [Supporting Information]

"FR901464: Total Synthesis, Proof of Structure, and Evaluation of Synthetic Analogs"  Thompson, C. F.; Jamison, T. F.; Jacobsen, E. N.  J. Am. Chem. Soc. 2001, 123, 9974–9983.  [Supporting Information 1, Supporting Information 2]

"Total Synthesis of Fostriecin (CI-920)"  Chavez, D. E.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2001, 40, 3667–3670.  [Supporting Information]

Jacobsen, E. N.; Tokunaga, M.; Larrow, J. F.  Hydrolytic Kinetic Resolution of Cyclic Substrates.  U.S. Patent #6262278 B1, July 17, 2001.

"Synthetically Useful, Self-Assembling MMO Mimic System for Catalytic Alkene Epoxidation with Aqueous H₂O₂"   White, M. C.; Doyle, A. G.; Jacobsen, E. N.  J. Am. Chem. Soc. 2001, 123, 7194–7195.  [Supporting Information]

"Regioselective Ring Opening of Enantiomerically Enriched Epoxides via Catalysis with Chiral (Salen)Cr(III) Complexes"  Brandes, B. D.; Jacobsen, E. N.  Synlett 2001, 1013–1015.

Jacobsen, E. N.; Schaus, S. E.; Dossetter, A. G.; Jamison, T. F.  Asymmetric Cycloaddition Reactions.  U.S. Patent #6211370, April 3, 2001.

"Highly Active Oligomeric (salen)Co Catalysts for Asymmetric Epoxide Ring Opening Reactions"  Ready, J. M.; Jacobsen, E. N.  J. Am. Chem. Soc. 2001, 123, 2687–2688.  [Supporting Information]

"Practical Synthesis of a Soluble Schiff Base Catalyst for the Asymmetric Strecker Reaction"  Su, J. T.; Vachal, P.; Jacobsen, E. N.  Adv. Synth. Catal. 2001, 343, 197–200.

"Practical Considerations in Kinetic Resolution Reactions"  Keith, J. M.; Larrow, J. F.; Jacobsen, E. N.  Adv. Synth. Catal. 2001, 343, 5–26.

"Total Synthesis of FR901464.Convergent Assembly of Chiral Components Prepared by Asymmetric Catalysis"  Thompson, C. F.; Jamison, T. F.; Jacobsen, E. N.  J. Am. Chem. Soc. 2000, 122, 10482–10483.  [Supporting Information]

Jacobsen, E. N.; Schaus, S. E.  Asymmetric Cycloaddition Reactions.  U.S. Patent #6130340, October 10, 2000.

"Cooperative Asymmetric Catalysis with Dendrimeric Co(salen) Complexes"  Breinbauer, R.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2000, 39, 3604–3607.

"Asymmetric Catalysis of Epoxide Ring-Opening Reactions"  Jacobsen, E. N.  Acc. Chem. Res. 2000, 33, 421–431.

"Asymmetric Ring-Opening of Meso-Epoxides with TMSCN Catalyzed by (pybox)Lanthanide Complexes"  Schaus, S. E.; Jacobsen, E. N.  Org. Lett. 2000, 2, 1001–1004.  [Supporting Information]

"Enantioselective Catalytic Addition of HCN to Ketoimines.Catalytic Synthesis of Quaternary Amino Acids"  Vachal, P.; Jacobsen, E. N.  Org. Lett. 2000, 2, 867–870.  [Supporting Information]

"A General Catalyst for the Asymmetric Strecker Reaction"   Sigman, M. S.; Vachal, P.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 2000, 39, 1279–1281.  [Supporting Information]

"Nickel Comes Full Cycle"  Jacobsen, E. N.; Breinbauer, R.  Science 2000, 287, 437–438 (Perspective).

"Enantioselective Ring-opening of meso Aziridines Catalyzed by Tridentate Schiff-base Chromium(III) Complexes"  Li, Z.; Fernandez, M.; Jacobsen, E. N.  Org. Lett. 1999, 1, 1611–1613.  [Supporting Information]

"Enantioselective Parallel Synthesis Using Polymer-Supported Chiral Co(Salen) Complexes"  Peukert, S.; Jacobsen, E. N.  Org. Lett. 1999, 1, 1245–1248.  [Supporting Information]

Jacobsen, E. N.  Future Perspectives in Asymmetric Catalysis.  In Comprehensive Asymmetric Catalysis; Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds.; Springer: New York, 1999; Chapter 42.

Jacobsen, E. N.  Aziridination.  In Comprehensive Asymmetric Catalysis; Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds.; Springer: New York, 1999; Chapter 17.

Jacobsen, E. N.; Wu, M. H.  Ring Opening of Epoxides and Related Reactions.  In Comprehensive Asymmetric Catalysis; Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds.; Springer: New York, 1999; Chapter 35.

Jacobsen, E. N.; Wu, M. H.  Epoxidation of Alkenes Other than Allylic Alcohols.  In Comprehensive Asymmetric Catalysis; Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds.; Springer: New York, 1999; Chapter 18.2.

"Asymmetric Synthesis of β-Amino Acid Derivatives via Catalytic Conjugate Addition of Hydrazoic Acid to Unsaturated Imides"  Myers, J. K.; Jacobsen, E. N.  J. Am. Chem. Soc. 1999, 121, 8959–8960.  [Supporting Information]

"Chromium Catalyzed Kinetic Resolution of 2,2-Disubstituted Epoxides"  Lebel, H.; Jacobsen, E. N.  Tetrahedron Lett. 1999, 40, 7303–7306.

"Highly Enantio- and Diastereoselective Hetero-Diels–Alder Reactions Catalyzed by New Chiral Tridentate Chromium Catalysts"  Dossetter, A. G.; Jamison, T. F.; Jacobsen, E. N.  Angew. Chem.,  Int. Ed. 1999, 38, 2398–2400.

Jacobsen, E. N.; Martinez, L. E.; Leighton, J. L.  Stereoselective Ring Opening Reactions.  U.S. Patent #5929232, July 27, 1999.

"Regio- and Enantioselective Cyclization of Epoxy Alcohols Catalyzed by a [CoIII(salen)] Complex"  Wu, M. H.; Hansen, K. B.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 1999, 38, 2012–2014.

"Asymmetric Catalytic Synthesis of α-Aryloxy Alcohols: Kinetic Resolution of Terminal Epoxides via Highly Enantioselective Ring Opening with Phenols"  Ready, J. M.; Jacobsen, E. N.  J. Am. Chem. Soc. 1999, 121, 6086–6087.  [Supporting Information 1, Supporting Information 2]

Senanayake, C. H.; Jacobsen, E. N.  Chiral (Salen)Mn(III) Complexes in Asymmetric Epoxidations: Practical Synthesis of cis-Aminoindanol and Its Application to Enantiopure Drug Synthesis.  In Process Chemistry in the Pharmaceutical Industry; Gadamasetti, K. G., Ed.; Dekker: New York, 1999; pp. 347–368.

"Polymer-Supported Chiral Co(Salen) Complexes: Synthetic Applications and Mechanistic Investigations in the Hydrolytic Kinetic Resolution of Terminal Epoxides"  Annis, D. A.; Jacobsen, E. N.  J. Am. Chem. Soc. 1999, 121, 4147–4154.

"Discovery of Novel Catalysts for Alkene Epoxidation Using Metal-Binding Combinatorial Libraries"  Francis, M. B.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 1999, 38, 937–941.

"Regioselective Carbomethoxylation of Chiral Epoxides: a New Route to Enantiomerically Pure β-Hydroxyesters" Hinterding, K.; Jacobsen, E.N.  J. Org. Chem. 1999, 64, 2164–2165.  [Supporting Information]

"(1S,2R)-1-Aminoindan-2-ol"  Larrow, J. F.; Roberts, E.; Verhoeven, T. R.; Ryan, K. M.; Senanayake, C. H.; Reider, P. J.; Jacobsen, E. N.  Org. Synth. 1998, 76, 46–56.

"Enantioselective Total Synthesis of Taurospongin A"  Lebel, H.; Jacobsen, E. N.  J. Org. Chem. 1998, 63, 9624–9625.  [Supporting Information 1, Supporting Information 2]

"Carbenoid Insertions into the Silicon-Hydrogen Bond Catalyzed by Chiral Copper (I) Schiff Base Complexes"  Dakin, L. A.; Schaus, S. E.; Jacobsen, E. N.; Panek, J. S.  Tetrahedron Lett. 1998, 39, 8947–8950.

"Cooperative Asymmetric Catalysis Using Dimeric Salen Complexes"  Konsler, R. G.; Karl, J.; Jacobsen, E. N.  J. Am. Chem. Soc. 1998, 120, 10780–10781.  [Supporting Information]

"Practical Access to Highly Enantioenriched C-3 Building Blocks via Hydrolytic Kinetic Resolution"  Furrow, M. E.; Schaus, S. E.; Jacobsen, E. N.  J. Org. Chem. 1998, 63, 6776–6777.  [Supporting Information]

"Solid Phase Synthesis of Cyclic RGD Peptide Derivatives via Asymmetric Catalysis: Stereochemistry as a Diversity Element"  Annis, D. A.; Jacobsen, E. N.  Angew. Chem., Int. Ed. 1998, 37, 1907–1909.

"Asymmetric Ring Opening of Meso Epoxides with Thiols: Enantiomeric Enrichment Using a Bifunctional Nucleophile"  Wu, M. H.; Jacobsen, E. N.  J. Org. Chem. 1998, 63, 5252–5254.  [Supporting Information]

"Total Synthesis of Muconin by Efficient Assembly of Chiral Building Blocks"  Schaus, S. E.; Brånalt, J. E.; Jacobsen, E. N.  J. Org. Chem. 1998, 63, 4876–4877.  [Supporting Information 1, Supporting Information 2]

"Combinatorial Libraries of Transition Metal Complexes, Catalysts, and Materials"  Francis, M. B.; Jamison, T. F.; Jacobsen, E. N.  Curr. Opin. Chem. Biol. 1998, 2, 422–428.

"Enantioselective Addition of Hydrogen Cyanide to Imines Catalyzed by a Chiral (salen)Al(III) Complex"  Sigman, M. S.; Jacobsen, E. N.  J. Am. Chem. Soc. 1998, 120, 5315–5316.  [Supporting Information]

"Schiff Base Catalysts for the Asymmetric Strecker Reaction Identified and Optimized from Parallel Synthetic Libraries"   Sigman, M. S.; Jacobsen, E. N.  J. Am. Chem. Soc. 1998, 120, 4901–4902.  [Supporting Information]

"The Mechanistic Basis for Electronic Effects on Enantioselectivity in the (salen)Mn-Catalyzed Epoxidation Reaction”  Palucki, M.; Finney, N. S.; Pospisil, P. J.; Güler, M. L.; Ishida, T.; Jacobsen, E. N.  J. Am. Chem. Soc. 1998, 120, 948–954.  [Supporting Information]

"Asymmetric Hetero-Diels–Alder Reactions Catalyzed by Chiral (salen)Chromium(III) Complexes"  Schaus, S. E.; Brånalt, J. E.; Jacobsen, E. N.  J. Org. Chem. 1998, 63, 403–405.  [Supporting Information]

"(R,R)-N,N'-Bis(3,5-Di-tert-butylsalicylidene)-1,2- Cyclohexanediaminomanganese (III) Chloride, a Highly Enantioselective Epoxidation Catalyst"  Larrow, J. F.; Jacobsen, E. N.  Org. Synth. 1997, 75, 1–10.

"Synthesis of Enantiopure 3-Chlorostyrene Oxide via an Asymmetric Epoxidation/Hydrolytic Kinetic Resolution Sequence"  Brandes, B. D.; Jacobsen, E. N.  Tetrahedron: Asymm. 1997, 8, 3927–3933.

Jacobsen, E. N.; Martinez, L. E.; Leighton, J. L.  Stereoselective Ring Opening Reactions.  U.S. Patent #5665890, September 9, 1997.

"On the Viability of Metallaoxetane Intermediates in the (salen)Mn-Catalyzed Asymmetric Epoxidation Reaction"  Finney, N. S.; Pospisil, P. J.; Chang, S.; Palucki, M.; Hansen, K. B.; Jacobsen, E. N.  Angew. Chem. Int. Ed. Engl. 1997, 36, 1720–1723.

"Asymmetric Catalysis with Water: Efficient Kinetic Resolution of Terminal Epoxides by Means of Catalytic Hydrolysis"  Tokunaga, M.; Larrow, J. F.; Kakiuchi, F.; Jacobsen, E. N.  Science 1997, 277, 936–938.

Jacobsen, E. N.; Zhang, W.; Deng, L.  Chiral Catalysts and Epoxidation Reactions.  U.S. Patent #5663393, September 2, 1997.

Jacobsen, E. N.; Zhang, W.; Deng, L.  Chiral Catalysts and Epoxidation Reactions Catalyzed Thereby.  U.S. Patent #5637739, June 10, 1997.

"Practical Synthesis of Enantiopure Cyclic 1,2-Aminoalcohols via Catalytic Asymmetric Ring Opening of Meso Epoxides"  Schaus, S. E.; Larrow, J. F.; Jacobsen, E. N.  J. Org. Chem. 1997, 62, 4197–4199.  [Supporting Information]

"An Efficient Formal Synthesis of Balanol via the Asymmetric Epoxide Ring Opening Reaction"  Wu, M. H.; Jacobsen, E. N.  Tetrahedron Lett. 1997, 38, 1693–1696.

"Enantioselective Catalytic Ring Opening of Epoxides with Carboxylic Acids"  Jacobsen, E. N.; Kakiuchi, F.; Konsler, R. G.; Larrow, J. F.; Tokunaga, M.  Tetrahedron Lett. 1997, 38, 773–776.

"On the Mechanism of Asymmetric Nucleophilic Ring-Opening of Epoxides Catalyzed by (Salen)Cr(III) Complexes"  Hansen, K. B.; Leighton, J. L.; Jacobsen, E. N.  J. Am. Chem. Soc. 1996, 118, 10924–10925.  [Supporting Information]

"Dynamic Kinetic Resolution of Epichlorohydrin via Enantioselective Catalytic Ring Opening with TMSN₃. Practical Synthesis of Aryl Oxazolidinone Antibacterial Agents"  Schaus, S. E.; Jacobsen, E. N.  Tetrahedron Lett. 1996, 37, 7937–7940.

"Highly Efficient and Enantioselective Synthesis of Carbocyclic Nucleoside Analogs Using Selective Early Transition Metal Catalysis"   Martinez, L. E.; Nugent, W. A.; Jacobsen, E. N.  J. Org. Chem. 1996, 61, 7963–7966.  

"Combinatorial Approach to the Discovery of Novel Coordination Compounds"  Francis, M. B.; Finney, N. S.; Jacobsen, E. N.  J. Am. Chem. Soc. 1996, 118, 8983–8984.  [Supporting Information]

"Enantioselective Binding of Prochiral Olefins to a Chiral Catalyst via Simultaneous Face-Face and Edge-Face Aromatic Interactions"  Quan, R. W.; Li, Z.; Jacobsen, E. N.  J. Am. Chem. Soc. 1996, 118, 8156–8157.  [Supporting Information]

"X-Ray Structural Studies of Highly Enantioselective Mn(salen) Epoxidation Catalysts"  Pospisil, P. J.; Carsten, D. H.; Jacobsen, E. N.  Chem. Eur. J. 1996, 2, 974–980.

"Kinetic Resolution of Terminal Epoxides via Highly Regioselective and Enantioselective Ring Opening with TMSN₃. An Efficient, Catalytic Route to 1,2-Aminoalcohols"  Larrow, J. F.; Schaus, S. E.; Jacobsen, E. N.  J. Am. Chem. Soc. 1996, 118, 7420–7421.  [Supporting Information]

"Efficient Synthesis of (R)-4-Trimethylsilyloxy-2- cyclopentenone by Enantioselective Catalytic Epoxide Ring Opening"  Leighton, J. L.; Jacobsen, E. N.  J. Org. Chem. 1996, 61, 389–390.  [Supporting Information]

"Kinetic Resolution of Racemic Chromenes via Asymmetric Epoxidation; Synthesis of (+)-Teretifolione B"  Vander Velde, S. L.; Jacobsen, E. N.  J. Org. Chem. 1995, 60, 5380–5381.  [Supporting Information 1, Supporting Information 2]

"Low Temperature Asymmetric Epoxidation of Unfunctionalized Olefins Catalyzed by (salen)Mn(III) Complexes"  Palucki, M.; McCormick, G. J.; Jacobsen, E. N.  Tetrahedron Lett. 1995, 36, 5457–5460.

"Enantioselective Catalytic Epoxidation of Tetrasubstituted Olefins"  Brandes, B. D.; Jacobsen, E. N.  Tetrahedron Lett. 1995, 36, 5123–5126.

Jacobsen, E. N.  Fundamental and Applied Studies in Asymmetric Oxidation Catalysis.  In Stereoselective Reactions of Metal-Activated Molecules; Werner, H., Sundmeyer, J., Eds.; Vieweg: New York, 1995; pp. 17–26.

Jacobsen, E. N.  Transition Metal Catalyzed Oxidations: Asymmetric Epoxidation.  In Comprehensive Organometallic Chemistry II; Wilkinson, G., Stone, F. G. A., Abel, E. W., Hegedus, L. S., Eds.; Pergamon: New York, 1995; Volume 12; pp. 1097–1135.

"Mechanistic Study of the (diimine)Cu-Catalyzed Asymmetric Azridination of Alkenes. Nitrene Transfer via Ligand-Accelerated Catalysis"  Li, Z.; Quan, R. W.; Jacobsen, E. N.  J. Am. Chem. Soc. 1995, 117, 5889–5890.  [Supporting Information]

"Highly Enantioselective Ring Opening of Epoxides Catalyzed by Chiral (salen)Cr(III) Complexes"  Martínez, L. E.; Leighton, J. L.; Carsten, D. H.; Jacobsen, E. N.  J. Am. Chem. Soc. 1995, 117, 5897–5898.  [Supporting Information]

Jacobsen, E. N.  Sodium Hypochlorite-Chiral Manganese (III) Salen Complexes.  In Encyclopedia of Reagents for Organic Synthesis; Paquette, L. A., Ed.; Wiley: New York, 1995; Volume 7; pp. 4585–4586.

Jacobsen, E. N.; Galvin, J. M.  Sodium Hypochlorite.  In Encyclopedia of Reagents for Organic Synthesis; Paquette, L.A., Ed.; Wiley: New York, 1995; Volume 7; pp. 4580–4585.

"Carbenoid Transfer to Imines: A New Asymmetric Catalytic Synthesis of Aziridines"  Hansen, K. H.; Finney, N. S.; Jacobsen, E. N.  Angew. Chem. Int. Ed. Engl. 1995, 34, 676–678.

"Synthetic and Biological Catalysts for Chemical Synthesis: How to Assess Practical Utility"  Jacobsen, E. N.; Finney, N. S.  Chem. Biol. 1994, 1, 85–90.

"Kinetic Resolution of 1,2-Dihydronaphthalene Oxide and Related Epoxides via Asymmetric C–H Hydroxylation"  Larrow, J. F.; Jacobsen, E. N.  J. Am. Chem. Soc. 1994, 116, 12129–12130.

"Highly Enantioselective, Low Temperature Epoxidation of Terminal Olefins"   Palucki, M.; Pospisil, P. J.; Zhang, W.; Jacobsen, E. N.  J. Am. Chem. Soc. 1994, 116, 9333–9334.  [Supporting Information]

"Highly Enantioselective, Catalytic Epoxidation of Trisubstituted Olefins"  Brandes, B. D.; Jacobsen, E. N.  J. Org. Chem. 1994, 59, 4378–4380.  [Supporting Information]

"Effect of Chiral Quaternary Ammonium Salts on (salen)Mn-Catalyzed Epoxidation of cis-Olefins. A Highly Enantioselective, Catalytic Route to Trans Epoxides"  Chang, S.; Galvin, J. M.; Jacobsen, E. N.  J. Am. Chem. Soc. 1994, 116, 6937–6938.  [Supporting Information]

"A Practical Process for the Large-Scale Preparation of (R,R)-N,N'-Bis(3,5-Di-tert-butylsalicylidene)-1,2-Cyclohexanediaminomanganese (III) Chloride, a Highly Enantioselective Epoxidation Catalyst"  Larrow, J. F.; Jacobsen, E. N.; Gao, Y.; Hong, Y.; Nie, X.; Zepp, C. M.  J. Org. Chem. 1994, 59, 1939–1940.  [Supporting Information]

"Enantioselective Epoxidation of Cyclic 1,3-Dienes Catalyzed by a Sterically and Electronically Optimized (Salen)Mn Complex"  Chang, S.; Heid, R. M.; Jacobsen, E. N.  Tetrahedron Lett. 1994, 35, 669–672.

"Enantioselective Catalytic Epoxidation of Cinnamate Esters"  Jacobsen, E. N.; Deng, L.; Furukawa, Y.; Martínez, L. E.  Tetrahedron 1994, 50, 4323–4334.

"Non-Stereospecific Mechanisms in Asymmetric Addition to Alkenes Result in Enantiodifferentiation after the First Irreversible Step"  Zhang, W.; Lee, N. H.; Jacobsen, E. N.  J. Am. Chem. Soc. 1994, 116, 425–426.  [Supporting Information]

"Regio- and Enantioselective Epoxidation of Conjugated Polyenes. Formal Synthesis of LTA4 Methyl Ester"  Chang, S.; Lee, N. H.; Jacobsen, E. N.  J. Org. Chem. 1993, 58, 6939–6941.  [Supporting Information]

"Synthesis and Characterization of Chiral Bimetallic Complexes Bearing Hard and Soft Lewis Acidic Sites"  Fields, L. B.; Jacobsen, E. N.  Tetrahedron: Asymm. 1993, 4, 2229–2240.

Jacobsen, E. N.  Asymmetric Catalytic Epoxidation of Unfunctionalized Olefins.  In Catalytic Asymmetric Synthesis; Ojima, I., Ed.; VCH: New York, 1993; Chapter 4.2.

"Encouraging Tomorrow's Chemists: University Outreach Program Bringing Hands-On Experiments to Local Students"  Heinze, K. F.; Allen, J. L.; Jacobsen, E. N.  J. Chem. Ed. 1995, 72, 167–169.

"Highly Enantioselective Epoxidation of Disubstituted Alkenes with Hydrogen Peroxide Catalyzed by Chloroperoxidase"  Allain, E. A.; Hager, L. P.; Deng, L.; Jacobsen, E. N.  J. Am. Chem. Soc. 1993, 115, 4415–4416.  [Supporting Information]

"Asymmetric Alkene Aziridination with Readily Available Chiral Diimine-Based Catalysts"  Li, Z.; Conser, K. R.; Jacobsen, E. N.  J. Am. Chem. Soc. 1993, 115, 5326–5327.  [Supporting Information]

"Salen-Manganese Complexes are Superoxide Dismutate Mimics"  Baudry, M.; Etienne, S.; Bruce, A.; Palucki, M.; Jacobsen, E.; Malfroy, B.  Biochem. Biophys. Res. Commun. 1993, 192, 964–968.

"Asymmetric Oxidation of Sulfides with H₂O₂-Catalyzed by (salen)Mn(III) Complexes"  Palucki, M.; Hanson, P.; Jacobsen, E. N.  Tetrahedron Lett. 1992, 33, 7111–7114.

"A Substoichiometric Pyridine•Lithium Enolate Complex: Solution and X-Ray Data, and Implications to Catalysis in the Aldol Reaction"  Pospisil, P. J.; Jacobsen, E. N.  J. Am. Chem. Soc. 1992, 114, 7585–7587.  [Supporting Information]

"A Practical, Highly Enantioselective Synthesis of the Taxol Side Chain via Asymmetric Catalysis"  Deng, L.; Jacobsen, E. N.  J. Org. Chem. 1992, 57, 4320–4323.

"Enantioselective Epoxidation of Conjugated Dienes and Enynes. Trans-Epoxides from Cis-Olefins"  Lee, N. H.; Jacobsen, E. N.  Tetrahedron Lett. 1991, 32, 6533–6536.

"Enantiomerically Pure Epoxychromans via Asymmetric Catalysis"  Lee, N. H.; Muci, A. R.; Jacobsen, E. N.  Tetrahedron Lett. 1991, 32, 5055–5058.

Jacobsen, E. N.  Asymmetric Synthesis.  In 1992 Yearbook of Science & Technology; McGraw-Hill, Inc.: New York, 1991; p 34.

"Electronic Tuning of Asymmetric Catalysts"  Jacobsen, E. N.; Güler, M. L.; Zhang, W.  J. Am. Chem. Soc. 1991, 113, 6703–6704.

"Mechanistic Study of a Synthetically Useful Mono-oxygenase Model Using Hypersensitive Probes cis and trans-2-phenyl-1-Vinylcyclopropane"  Fu, H.; Look, G. C.; Zhang, W.; Jacobsen, E. N.; Wong, C.-H.  J. Org. Chem. 1991, 56, 6497–6500.  [Supporting Information]

"Highly Enantioselective Epoxidation Catalysts Derived from 1,2-Diaminocyclohexane"  Jacobsen, E. N.; Zhang, W.; Muci, A. R.; Ecker, J. R.; Deng, L.  J. Am. Chem. Soc. 1991, 113, 7063–7064.  [Supporting Information]

"Asymmetric Epoxidation with Sodium Hypochlorite Catalyzed by Readily Available Chiral Mn(III) Salen Complexes"  Zhang, W.; Jacobsen, E. N.  J. Org. Chem. 1991, 56, 2296–2298.  [Supporting Information]

"Preparation of trans-1,2-Diamino-1,2-Dimethylcyclohexane via Highly Stereoselective Olefin Oxidation by Dinitrogen Tetroxide"  Zhang, W.; Jacobsen, E. N.  Tetrahedron Lett. 1991, 32, 1711–1714.

"Enantioselective Epoxidation of Unfunctionalized Olefins Catalyzed by (salen)Manganese Complexes"  Zhang, W.; Loebach, J. L.; Wilson, S. R.; Jacobsen, E. N.  J. Am. Chem. Soc. 1990, 112, 2801–2803.

"On the Structure of Osmium Tetroxide-Cinchona Alkaloid Complexes"  Svendsen, J. S.; Markó, I. E.; Jacobsen, E. N.; Pulla Rao, Ch.; Bott, S.; Sharpless, K. B.  J. Org. Chem. 1989, 54, 2263.

"A Mechanistic Insight Leads to a Greatly Improved Osmium-Catalyzed Asymmetric Dihydroxylation Process"  Wai, J. S. M.; Markó, I. E.; Svendsen, J. S.; Finn, M. G.; Jacobsen, E. N.; Sharpless, K. B.  J. Am. Chem. Soc. 1989, 111, 1123.

"Kinetic Role of Alkaloid Ligands in Asymmetric Catalytic Dihydroxylation" Jacobsen, E. N.; Markó, I. E.; France, M. B.; Svendsen, J. S.; Sharpless, K. B.  J. Am. Chem. Soc. 1989, 111, 737.

"Rapid, Reversible Intramolecular C–H Oxidative Addition and H-Exchange in a Heterodinuclear 'Early-Late' Transition Metal Complex"  Jacobsen, E. N.; Goldberg, K. I.; Bergman, R. G.  J. Am. Chem. Soc. 1988, 110, 3706.

"Asymmetric Dihydroxylation via Ligand-Accelerated Catalysis" Jacobsen, E. N.; Markó, I. E.; Mungall, W. S.; Schröder, G. W.; Sharpless, K. B.  J. Am. Chem. Soc. 1988, 110, 1968.

"Synthesis of Organometallic Heterodinuclear µ-Oxo Complexes by Extrusion of Alkenes from Zirconium/Tungsten Oxaalkyl Complexes" Jacobsen, E. N.; Trost, M. K.; Bergman, R. G.  J. Am. Chem. Soc. 1986, 108, 8092.

"Synthesis and Chemistry of a Bridging Vinylidenedicobalt Complex. Evidence for a Non-Chain Radical Mechanism in its Reaction with Metal Hydrides to Give Heteronuclear Clusters" Jacobsen, E. N.; Bergman, R. G.  J. Am. Chem. Soc. 1985, 107, 2023.

"Steric Effects on the Titanium Tetrachloride-Promoted Dimerization of Silyl Ketene Acetals" Jacobsen, E. N.; Totten, G. E.; Wenke, G.; Karydas, A. C.; Rhodes, Y. E.  Synth. Commun. 1985, 15, 301.

"Synthesis, Crystal and Molecular Structure, and Reactions of the Bridging Vinylidenedicobalt Complex (µ-CCH₂)(CpCoCO)₂. Reaction with Molybdenum Hydrides to Give a Heteronuclear Cluster Complex" Jacobsen, E. N.; Bergman, R. G.  Organometallics 1984, 3, 329.

"Silyl Ketene Acetal Chemistry: Steric Limitations in Lewis Acid-Promoted Addition of Ketones" Wenke, G.; Jacobsen, E. N.; Totten, G. E.; Karydas, A. C.; Rhodes, Y. E.  Synth. Commun. 1983, 13, 449.